Avascular necrosis (AVN), also called osteonecrosis, is a condition in which the bone of the femoral head (the “ball” of the hip) loses its blood supply. Without blood flow, the bone weakens and can eventually collapse, flattening the ball and causing arthritis. The earlier AVN is found, the more options there are to protect the natural hip.
- Deep groin or front-of-hip pain, often without an injury
- X-rays can look normal early on; MRI finds it sooner
- It often affects both hips, so the other hip is checked too
- Before the ball collapses, core decompression can help preserve the hip
- After collapse, hip replacement reliably relieves pain
What causes avascular necrosis?
AVN results from anything that interrupts blood flow to the femoral head. Common risk factors include:5
- High-dose or long-term corticosteroid (steroid) use
- Heavy alcohol use
- Hip fractures and dislocations
- Sickle cell disease and other blood disorders
- Lupus and other conditions that affect blood vessels or clotting
- Radiation treatment and decompression sickness (“the bends”)
In some patients, no cause is found. This is called idiopathic AVN.
Symptoms
Most people notice a gradual, deep ache in the groin or front of the hip that is worse with standing and walking. As the condition progresses, pain can occur at rest or at night, and the hip may become stiff. Some people have no symptoms in the early stages, which is one reason the other hip is checked when AVN is found.
Diagnosis and staging
Dr. Dold starts with a history, an exam and X-rays, which can often be done at the same visit. Because early AVN may not show on X-rays, an MRI is the most sensitive test. Treatment depends on the stage, and in particular on whether the ball has started to collapse:
- Early (pre-collapse): the bone is affected, but the ball is still round.
- Collapse: the weakened bone has begun to flatten.
- Late: the joint surface is damaged and arthritis has developed.
Treatment before collapse: core decompression
When AVN is found before the ball collapses, the goal is to save the natural hip. Treatment may include protected weight bearing, addressing risk factors (for example, reviewing steroid or alcohol use with your other doctors) and, for many patients, core decompression.
Core decompression is a minimally invasive, outpatient procedure. Through a small incision on the side of the thigh and using live X-ray guidance, Dr. Dold drills one or more small channels into the affected area of the femoral head. This relieves pressure inside the bone and encourages new blood vessels to grow. The channel may also be filled with bone graft material (such as calcium phosphate, calcium sulfate or demineralized bone matrix) and/or a concentrate of your own bone marrow (BMAC).
After surgery, most patients use crutches for about 6 to 8 weeks to protect the bone while it heals, followed by a gradual return to activity. Results are better when AVN is treated early, while the affected area is small.2
Treatment after collapse: hip replacement
Once the femoral head has collapsed or arthritis has developed, core decompression is less likely to help. A total hip replacement reliably relieves pain and restores function. Dr. Dold specializes in direct anterior hip replacement, a muscle-sparing approach that is usually done as outpatient surgery with no traditional hip precautions.
Watch Dr. Dold: core decompression
Some of these videos show real surgery, so some viewers may prefer not to watch.
More videos on Dr. Dold’s YouTube channel.
Why early evaluation matters
AVN tends to progress. If you have deep groin pain and a risk factor such as steroid use, don’t wait for it to get worse. An MRI can find AVN while hip-preserving treatment is still an option.
- AVN often progresses, even without symptoms. In a review of 16 studies (664 hips) where AVN was found before symptoms began, 59% went on to develop symptoms or collapse. Small lesions on the inner side of the femoral head had the lowest risk, with collapse in fewer than 10%.1
- Early treatment does better. After core decompression with multiple small drillings, 79% of patients with small, early-stage (Ficat stage I) lesions showed no progression on X-ray.2
- Adding your own bone marrow cells. A 2023 analysis of 18 studies found lower rates of disease progression and of conversion to hip replacement when a concentrate of the patient’s own bone marrow cells was added to core decompression, compared with core decompression alone. Results were less favorable in older patients and after collapse.3
- Hip replacement for AVN does well. Across 67 reports (3,277 hips), revision rates fell from 17% for operations before 1990 to 3% for those done in 1990 or later, similar to national joint registry results.4 A 2020 review concluded that hip replacement results in AVN are similar to those in osteoarthritis.5
What the research shows
Here is what published studies show about AVN of the hip, its risk factors and treatment.
Risk factors and early diagnosis
Corticosteroid use and alcohol are two of the most consistent risk factors, and the risk with alcohol rises with the amount consumed. MRI finds AVN before it shows on X-rays, which matters because results of hip-preserving treatment depend heavily on catching the disease before the ball collapses.
Core decompression and biologic augmentation
Several meta-analyses of randomized and comparative studies have found that adding a concentrate of the patient’s own bone marrow cells to core decompression improves pain and function and reduces progression to hip replacement compared with core decompression alone. The quality of these studies varies, so results should be viewed as encouraging rather than definitive. Other hip-preserving options, such as vascularized bone grafts and osteotomies, are performed at specialized centers and have more variable results.
Medicines and shock wave therapy
A randomized trial found that a bisphosphonate (zoledronate) did not prevent collapse. Shock wave therapy has relieved pain in early-stage AVN in some studies but has not been shown to heal the affected bone.
Hip replacement
When the femoral head has collapsed, hip replacement reliably relieves pain. Revision rates after replacement for AVN are somewhat higher than after replacement for osteoarthritis.
Why see Dr. Dold
- Hip arthroscopy research in AJSM and JBJS Reviews; Stryker Advanced Hip Arthroscopy Course (2018)
- Board certified by the American Board of Orthopaedic Surgery, with subspecialty certification in Sports Medicine
- Fellow of the American Orthopaedic Association (FAOA), the American Academy of Orthopaedic Surgeons (FAAOS), the American College of Surgeons (FACS) and the Royal College of Surgeons of Canada (FRCSC)
- Sports medicine and arthroscopy fellowship at NYU Langone / Hospital for Joint Diseases; orthopedic residency at the University of Toronto
- Member of the International Society for Hip Arthroscopy (ISHA)
- D Magazine Best Doctors (Collin County), 2019–2026 · Rated 4.9 on Google
Frequently asked questions
What is the first sign of avascular necrosis of the hip?
Usually a gradual, deep ache in the groin or front of the hip that is worse with standing and walking. Early AVN can also cause no symptoms at all.
Can avascular necrosis of the hip heal on its own?
Small, early areas sometimes stabilize, but AVN often progresses. Early treatment gives you more options to save the natural hip.
What is core decompression surgery?
An outpatient procedure that drills small channels into the affected bone to relieve pressure and encourage new blood flow. It is used before the ball of the hip collapses.
How long is recovery after core decompression?
Most patients use crutches for about 6 to 8 weeks to protect the bone, then gradually return to normal activity.
Will I need a hip replacement for AVN?
Not always. If the ball of the hip has not collapsed, core decompression may preserve it. If it has collapsed or arthritis has developed, hip replacement is usually the most reliable treatment.
Research cited on this page
- Mont MA, Zywiel MG, Marker DR, et al. The natural history of untreated asymptomatic osteonecrosis of the femoral head: a systematic literature review. J Bone Joint Surg Am. 2010;92(12):2165-2170. PubMed
- Marker DR, Seyler TM, Ulrich SD, et al. Do modern techniques improve core decompression outcomes for hip osteonecrosis? Clin Orthop Relat Res. 2008;466(5):1093-1103. PubMed
- Saini U, Jindal K, Rana A, et al. Core decompression combined with intralesional autologous bone marrow derived cell therapies for osteonecrosis of the femoral head in adults: a systematic review and meta-analysis. Surgeon. 2023;21(3):e104-e117. PubMed
- Johannson HR, Zywiel MG, Marker DR, et al. Osteonecrosis is not a predictor of poor outcomes in primary total hip arthroplasty: a systematic literature review. Int Orthop. 2011;35(4):465-473. PubMed
- Mont MA, Salem HS, Piuzzi NS, et al. Nontraumatic osteonecrosis of the femoral head: where do we stand today? A 5-year update. J Bone Joint Surg Am. 2020;102(12):1084-1099. PubMed
- Roth A, Beckmann J, Bohndorf K, et al. S3-Guideline non-traumatic adult femoral head necrosis. Arch Orthop Trauma Surg. 2016;136(2):165-74. PubMed
A national guideline recommends X-rays first and MRI when X-rays are normal, with staging used to guide treatment. - Nevskaya T, Gamble MP, Pope JE. A meta-analysis of avascular necrosis in systemic lupus erythematosus: prevalence and risk factors. Clin Exp Rheumatol. 2017;35(4):700-710. PubMed
A meta-analysis found AVN affects about a third of people with lupus, and higher-dose corticosteroid use early in the disease is a risk factor. - Yoon BH, Kim TY, Shin IS, et al. Alcohol intake and the risk of osteonecrosis of the femoral head in Japanese populations: a dose-response meta-analysis of case-control studies. Clin Rheumatol. 2017;36(11):2517-2524. PubMed
Current alcohol use was linked to a higher risk of hip AVN, rising with the amount consumed. - Parikh RR, Mirzaei A, Butler ME, et al. Diagnosis and Treatment of Nontraumatic Osteonecrosis of the Femoral Head: A Systematic Review and Meta-Analyses for the ARCO Clinical Practice Guideline Development Workgroup. Med Sci (Basel). 2026;14(1). PubMed
A 2026 review found the evidence for imaging choices and early hip-preserving treatments remains mostly observational. - Migliorini F, Maffulli N, Baroncini A, et al. Prognostic factors in the management of osteonecrosis of the femoral head: A systematic review. Surgeon. 2023;21(2):85-98. PubMed
Male sex, longer symptoms before treatment and worse pain and function scores predicted poorer results after AVN treatment. - Liu Q, Guo W, Li R, et al. Efficacy of various core decompression techniques versus non-operative treatment for osteonecrosis of the femoral head: a systemic review and network meta-analysis of randomized controlled trials. BMC Musculoskelet Disord. 2021;22(1):948. PubMed
A network meta-analysis of 17 randomized trials found core decompression combined with cell therapy slowed X-ray progression compared with other options. - Zhang C, Fang X, Huang Z, et al. Addition of Bone Marrow Stem Cells Therapy Achieves Better Clinical Outcomes and Lower Rates of Disease Progression Compared With Core Decompression Alone for Early Stage Osteonecrosis of the Femoral Head: A Systematic Review and Meta-Analysis. J Am Acad Orthop Surg. 2020;28(23):973-979. PubMed
Adding bone marrow cells to core decompression lowered pain and improved hip scores at 2 years compared with core decompression alone, though study quality was variable. - Migliorini F, Maffulli N, Eschweiler J, et al. Core decompression isolated or combined with bone marrow-derived cell therapies for femoral head osteonecrosis. Expert Opin Biol Ther. 2021;21(3):423-430. PubMed
Over about 7 years, core decompression with bone marrow cell therapy led to less pain and fewer hip replacements than core decompression alone. - Xiang XN, Wang HN, He HC, et al. Bone Marrow-Derived Cell Therapy Plus Core Decompression Enhanced Efficacy Compared With Core Decompression Alone in Treating Osteonecrosis of the Femoral Head: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Arthroscopy. 2026;42(10):2275-2290. PubMed
A 2026 meta-analysis found core decompression plus bone marrow-derived cell therapy improved pain, function and hip survival compared with core decompression alone, with limited evidence quality. - Ouyang W, Guo G, Xia J, et al. Arthroscopic assisted versus open core decompression for osteonecrosis of the femoral head: A systematic review and meta-analysis. PLoS One. 2024;19(11):e0313265. PubMed
Arthroscopic-assisted and standard core decompression had similar complication rates and early hip scores. - Fang T, Zhang EW, Sailes FC, et al. Vascularized fibular grafts in patients with avascular necrosis of femoral head: a systematic review and meta-analysis. Arch Orthop Trauma Surg. 2013;133(1):1-10. PubMed
Vascularized fibular grafting reduced collapse and conversion to hip replacement compared with other methods in a meta-analysis, mostly in earlier stages. - Quaranta M, Miranda L, Oliva F, et al. Osteotomies for avascular necrosis of the femoral head. Br Med Bull. 2021;137(1):98-111. PubMed
Across 852 hip osteotomies for AVN, about a third were converted to hip replacement, and no randomized trials were available. - Lee YK, Ha YC, Cho YJ, et al. Does Zoledronate Prevent Femoral Head Collapse from Osteonecrosis? A Prospective, Randomized, Open-Label, Multicenter Study. J Bone Joint Surg Am. 2015;97(14):1142-8. PubMed
A randomized trial found zoledronate (a bisphosphonate) did not prevent femoral head collapse or reduce the need for hip replacement. - Mei J, Pang L, Jiang Z. The effect of extracorporeal shock wave on osteonecrosis of femoral head: a systematic review and meta-analysis. Phys Sportsmed. 2022;50(4):280-288. PubMed
A meta-analysis found shock wave therapy improved pain and hip scores in early AVN but did not shrink the affected area. - Martí-Carvajal AJ, Solà I, Agreda-Pérez LH. Treatment for avascular necrosis of bone in people with sickle cell disease. Cochrane Database Syst Rev. 2019;12(12):CD004344. PubMed
A Cochrane review in sickle cell disease found no clear evidence that adding core decompression to physical therapy improved results. - Fassihi SC, Lee R, Quan T, et al. Total Hip Arthroplasty in Patients With Sickle Cell Disease: A Comprehensive Systematic Review. J Arthroplasty. 2020;35(8):2286-2295. PubMed
Hip replacement improved function in patients with sickle cell disease, though medical complications and readmissions were more common. - Salman LA, Hantouly AT, Khatkar H, et al. The outcomes of total hip replacement in osteonecrosis versus osteoarthritis: a systematic review and meta-analysis. Int Orthop. 2023;47(12):3043-3052. PubMed
A meta-analysis of over 2 million hips found hip replacement for AVN had a somewhat higher revision rate than for osteoarthritis, with similar dislocation rates. - Kim SJ, Kang DG, Park SB, et al. Is Hemiresurfacing Arthroplasty for Osteonecrosis of the Hip a Viable Solution?. J Arthroplasty. 2015;30(6):987-92. PubMed
Partial resurfacing of the femoral head for AVN had a 74% success rate and about 1 in 5 needed revision.
Medically reviewed by Andrew P. Dold, MD, FAOA, FAAOS, FACS, FRCSC. Last reviewed October 4, 2026. This page is general information, not medical advice.









